Cyp2r1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Cyp2r1^{tm1(KOMP)Vlcg}
• Name: cytochrome P450, family 2, subfamily r, polypeptide 1; targeted mutation 1, Velocigene
• MGI ID: MGI:3808340
• Synonyms: Cyp2r1^-, Cyp2r1^tm1Vlcg
• Gene: Cyp2r1 Location: Chr7:114149358-114162283 bp, - strand Genetic Position: Chr7, 59.79 cM
• Alliance: Cyp2r1^{tm1(KOMP)Vlcg} page
• IMPC: Cyp2r1 gene page

Mutation origin

• Mutant Cell Lines: 10568A-D10, 10568A-E11, 10568A-G3
• Germline Transmission: Earliest citation of germline transmission: J:223194
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: A 12.9-kb span between positions 114149312-114162189 of Chromosome 7 (Build GRCm39), which covers all 5 exons of the gene, was replaced with a beta-galactosidase coding sequence (lacZ) and a neomycin selection cassette. (J:136110, J:223194)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 1 line available
• Carrying any Cyp2r1 Mutation: 27 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 2 reference(s)