E2f3^tm2Gle
Targeted Allele Detail

Summary

• Symbol: E2f3^tm2Gle
• Name: E2F transcription factor 3; targeted mutation 2, Gustavo Leone
• MGI ID: MGI:3806810
• Gene: E2f3 Location: Chr13:30090558-30170046 bp, - strand Genetic Position: Chr13, 13.09 cM, cytoband A3.3
• Alliance: E2f3^tm2Gle page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138289
• Parent Cell Line: TC1/TC-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neo cassette was inserted 108 bp upstream of the E2f3a isofrom start codon and a third loxP site was inserted approximately 300 bp downstream of exon 1a. (J:138289)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any E2f3 Mutation: 32 strains or lines available

References

• Original: J:138289 Tsai SY, et al., Mouse development with a single E2F activator. Nature. 2008 Aug 28;454(7208):1137-41
• All: 1 reference(s)