Tg(RHO-VEGFA)V-24Camp
Transgene Detail

Summary

• Symbol: Tg(RHO-VEGFA)V-24Camp
• Name: transgene insertion V-24,Peter A Campochiaro
• MGI ID: MGI:3806312
• Synonyms: V-24
• Transgene: Tg(RHO-VEGFA)V-24Camp Location: unknown
• Alliance: Tg(RHO-VEGFA)V-24Camp page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(RHO-VEGFA)V-24Camp expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  VEGFA (7422)

  Vegfa

  (MGI:103178)

• Mutation details: This transgene consists of a 2.2 kb fragment of the bovine rhodopsin promoter driving expression of a full length human VEGFA cDNA followed by an intron and polyA site from the mouse protamine gene. Thirteen to fifteen copies of the transgene were incorporated in this line. MRNA expression analysis detected a modest signal at P7, a strong signal at P14, and only faint expression at 3 months of age in the retinas of hemizygous mice. (J:41411)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:41411 Okamoto N, et al., Transgenic mice with increased expression of vascular endothelial growth factor in the retina: a new model of intraretinal and subretinal neovascularization [see comments]. Am J Pathol. 1997 Jul;151(1):281-91
• All: 5 reference(s)