Padi6^tm1Jgo
Targeted Allele Detail

Summary

• Symbol: Padi6^tm1Jgo
• Name: peptidyl arginine deiminase, type VI; targeted mutation 1, Jan A Gossen
• MGI ID: MGI:3806008
• Gene: Padi6 Location: Chr4:140454666-140469954 bp, - strand Genetic Position: Chr4, 72.26 cM, cytoband E1
• Alliance: Padi6^tm1Jgo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:138684
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an frt-flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. (J:138684)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Padi6 Mutation: 32 strains or lines available

References

• Original: J:138684 Esposito G, et al., Peptidylarginine deiminase (PAD) 6 is essential for oocyte cytoskeletal sheet formation and female fertility. Mol Cell Endocrinol. 2007 Jul 15;273(1-2):25-31
• All: 1 reference(s)