Kif11^tm1Much
Targeted Allele Detail

Summary

• Symbol: Kif11^tm1Much
• Name: kinesin family member 11; targeted mutation 1, Muriel Chauviere
• MGI ID: MGI:3803280
• Synonyms: Eg5^-
• Gene: Kif11 Location: Chr19:37364851-37410307 bp, + strand Genetic Position: Chr19, 32.27 cM
• Alliance: Kif11^tm1Much page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137799
• Parent Cell Line: CK35 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exon 2 and part of exon 3 were replaced with a cassette containing an IRES and beta-geo cassette. (J:137799)

Expression

In Mice Carrying this Mutation:	32 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kif11 Mutation: 59 strains or lines available

References

• Original: J:137799 Chauviere M, et al., Disruption of the mitotic kinesin Eg5 gene (Knsl1) results in early embryonic lethality. Biochem Biophys Res Commun. 2008 Aug 8;372(4):513-9
• All: 1 reference(s)