Tg(Lcn2-Prl)23Eps
Transgene Detail

Summary

• Symbol: Tg(Lcn2-Prl)23Eps
• Name: transgene insertion 23, Eric P Sandgren
• MGI ID: MGI:3802725
• Synonyms: line 1647-13, TgN(Nrl-Prl)23EPS
• Transgene: Tg(Lcn2-Prl)23Eps Location: unknown
• Alliance: Tg(Lcn2-Prl)23Eps page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Lcn2-Prl)23Eps expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Prl (24683)

  Prl	(MGI:97762)

• Mutation details: The rat lipocalin 2 (also called NRL2, neu-related lipocalin) promoter drives expression of a rat prolactin cDNA in epithelial cells of the mammary gland. (J:84986)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Lcn2-Prl)23Eps

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:84986 Rose-Hellekant TA, et al., Prolactin induces ERalpha-positive and ERalpha-negative mammary cancer in transgenic mice. Oncogene. 2003 Jul 24;22(30):4664-74
• All: 8 reference(s)