Atoh8^{tm1(EGFP/cre)Gasa}
Targeted Allele Detail

Summary

• Symbol: Atoh8^{tm1(EGFP/cre)Gasa}
• Name: atonal bHLH transcription factor 8; targeted mutation 1, Rosa Gasa
• MGI ID: MGI:3799350
• Synonyms: Atoh8^deltaex1-2, Math6^EGFP-Cre
• Gene: Atoh8 Location: Chr6:72183161-72212561 bp, - strand Genetic Position: Chr6, 32.27 cM
• Alliance: Atoh8^{tm1(EGFP/cre)Gasa} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137207
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Recombinase, Reporter)
• Mutations: Insertion, Intragenic deletion
• Atoh8^{tm1(EGFP/cre)Gasa} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Atoh8 (MGI:1918343)

• Mutation details: An EGFP/cre fusion and frt-flanked neo cassette were knocked into the gene replacing exons 1 and 2. Germ line, flp-mediated recombination was used to remove the neo cassette. (J:137207)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Atoh8 (mouse) Summary of all recombinase alleles driven by Atoh8. Comparative matrix view of recombinase activities Alliance mouse Atoh8 gene page

Expression

In Mice Carrying this Mutation:

41 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Atoh8 Mutation: 7 strains or lines available

References

• Original: J:137207 Lynn FC, et al., Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One. 2008;3(6):e2430
• All: 4 reference(s)