Kiz^tm1.1Cpl
Targeted Allele Detail

Summary

• Symbol: Kiz^tm1.1Cpl
• Name: kizuna centrosomal protein; targeted mutation 1.1, Blanche Capel
• MGI ID: MGI:3797918
• Gene: Kiz Location: Chr2:146697784-146812017 bp, + strand Genetic Position: Chr2, 72.63 cM
• Alliance: Kiz^tm1.1Cpl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136802
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 5 and 6 corresponding to 950 bp coding sequence are removed after crossing Gm114^tm1Cpl heterozygous mice with cre expressing mice leaving a single loxP site in place and generating a stop codon the beginning of exon 7. Truncated transcripts were expressed in testes, however western blot confirmed no C-terminal end containing protein were expressed. (J:136802)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kiz Mutation: 37 strains or lines available

References

• Original: J:136802 Tang H, et al., Expression and functional analysis of Gm114, a putative mammalian ortholog of Drosophila bam. Dev Biol. 2008 Jun 1;318(1):73-81
• All: 1 reference(s)