Hs6st2^tm1Kkm
Targeted Allele Detail

Summary

• Symbol: Hs6st2^tm1Kkm
• Name: heparan sulfate 6-O-sulfotransferase 2; targeted mutation 1, Koji Kimata
• MGI ID: MGI:3797641
• Gene: Hs6st2 Location: ChrX:50476084-50770643 bp, - strand Genetic Position: ChrX, 28.04 cM, cytoband A3.3
• Alliance: Hs6st2^tm1Kkm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:136555
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 1, containing the PAPS-binding domain, was floxed. (J:136555)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hs6st2 Mutation: 7 strains or lines available

References

• Original: J:136555 Sugaya N, et al., 6-O-sulfation of heparan sulfate differentially regulates various fibroblast growth factor-dependent signalings in culture. J Biol Chem. 2008 Apr 18;283(16):10366-76
• All: 2 reference(s)