Kmt5a^{Gt(RRB075)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Kmt5a^{Gt(RRB075)Byg}
• Name: lysine methyltransferase 5A; gene trap RRB075, BayGenomics
• MGI ID: MGI:3796614
• Gene: Kmt5a Location: Chr5:124577993-124600371 bp, + strand Genetic Position: Chr5, 63.59 cM
• Alliance: Kmt5a^{Gt(RRB075)Byg} page

Mutation origin

• Mutant Cell Line: RRB075
• Germline Transmission: Earliest citation of germline transmission: J:136565
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1Lxf Vector Type: gene trap
• The gene trap vector containing a neo cassette was inserted into intron 3. (J:136565)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RRB075	CC183250 ; (MGI Seq Detail)	5' RACE	Chr5:124577988-124585430 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  68 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kmt5a Mutation: 47 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:136565 Huen MS, et al., Direct interaction between SET8 and proliferating cell nuclear antigen couples H4-K20 methylation with DNA replication. J Biol Chem. 2008 Apr 25;283(17):11073-7
• All: 3 reference(s)