Faf1^Gt(2C98)Wen
Gene trapped Allele Detail

Summary

• Symbol: Faf1^Gt(2C98)Wen
• Name: Fas-associated factor 1; gene trap 2C98, Wolfgang Engel
• MGI ID: MGI:3795251
• Synonyms: Faf1^GT
• Gene: Faf1 Location: Chr4:109533873-109821157 bp, + strand Genetic Position: Chr4, 51.33 cM, cytoband C6
• Alliance: Faf1^Gt(2C98)Wen page

Mutation origin

• Mutant Cell Line: 2C98
• Germline Transmission: Earliest citation of germline transmission: J:135886
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pMS1 Vector Type: gene trap
• Mutation details: A gene trap vector inserted into intron 7. RT-PCR analysis indicated that an aberrantly spliced transcript is expressed from this allele, resulting in a frameshift and premature termination of translation within sequences corresponding to exon 8. (J:135886)

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Faf1 Mutation: 97 strains or lines available

Notes

Gene traps generated from the same library were created in 129/Sv cells.

References

• Original: J:135886 Adham IM, et al., Fas-associated factor (FAF1) is required for the early cleavage-stages of mouse embryo. Mol Hum Reprod. 2008 Apr;14(4):207-13
• All: 1 reference(s)