Plxnb1^tm1Ltam
Targeted Allele Detail

Summary

• Symbol: Plxnb1^tm1Ltam
• Name: plexin B1; targeted mutation 1, Luca Tamagnone
• MGI ID: MGI:3790772
• Gene: Plxnb1 Location: Chr9:108924457-108948985 bp, + strand Genetic Position: Chr9, 59.63 cM
• Alliance: Plxnb1^tm1Ltam page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:134426
• Parent Cell Line: W9.5/W95 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A cassette containing a 5'loxP site, an frt-flanked neo cassette and a lacZ cassette was inserted downstream of exon 23. An additional loxP site was inserted upstream of exon 22. (J:134426)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plxnb1 Mutation: 108 strains or lines available

References

• Original: J:134426 Fazzari P, et al., Plexin-B1 plays a redundant role during mouse development and in tumour angiogenesis. BMC Dev Biol. 2007;7:55
• All: 1 reference(s)