Tg(Gata1-NS1)468Sug
Transgene Detail

Summary

• Symbol: Tg(Gata1-NS1)468Sug
• Name: transgene insertion 468, Kazuo Sugamura
• MGI ID: MGI:3784512
• Synonyms: GATA1-Neo-NS1, IE3.9int-loxP-neo-loxP-NS1
• Transgene: Tg(Gata1-NS1)468Sug Location: unknown
• Alliance: Tg(Gata1-NS1)468Sug page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The Gata1 promoter region IE3.9 drives erythrocyte-specific expression of NS1 gene from human parvovirus B19. A floxed-neo cassette positioned between the promoter and the gene prevents expression unless excised. Three lines were created (464, 468 and 175) with line 468 chosen as the representative line. (J:133736)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:133736 Chisaka H, et al., A transgenic mouse model for non-immune hydrops fetalis induced by the NS1 gene of human parvovirus B19. J Gen Virol. 2002 Feb;83(Pt 2):273-81
• All: 1 reference(s)