Pclo^tm3.1Sud
Targeted Allele Detail

Summary

• Symbol: Pclo^tm3.1Sud
• Name: piccolo (presynaptic cytomatrix protein); targeted mutation 3.1, Thomas C Sudhof
• MGI ID: MGI:3783987
• Synonyms: PIF
• Gene: Pclo Location: Chr5:14564932-14913473 bp, + strand Genetic Position: Chr5, 6.27 cM, cytoband A2
• Alliance: Pclo^tm3.1Sud page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:133655
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A targeting vector was used to introduce D4668A and D4674A mutations in the gene. A component FRT-flanked neomycin resistance cassette was removed through a cross with a C57BL/6-background FLP mouse. (J:133655)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pclo Mutation: 267 strains or lines available

References

• Original: J:133655 Sudhof TC, Generation of a Pclo knock-in allele. MGI Direct Data Submission. 2008
• All: 2 reference(s)