Myf6tm2(cre)Mrc
Targeted Allele Detail
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Symbol: |
Myf6tm2(cre)Mrc |
Name: |
myogenic factor 6; targeted mutation 2, Mario R Capecchi |
MGI ID: |
MGI:3783305 |
Synonyms: |
Myf6-ICN-, Myf6-ICNp |
Gene: |
Myf6 Location: Chr10:107328709-107330584 bp, - strand Genetic Position: Chr10, 55.96 cM
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Alliance: |
Myf6tm2(cre)Mrc page
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Allele Type: |
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Targeted (Hypomorph, Recombinase) |
Mutation: |
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Insertion
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Myf6tm2(cre)Mrc expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Myf6 (MGI:97253) |
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Mutation details: An IRES-Cre and frt-flanked neo cassette were inserted in the 3' UTR to allow bicistronic expression of Myf6 and Cre. Myf6tm1(cre)Mrc was generated from this allele. Reduced transcript expression was confirmed by semi-quantitative RT-PCR at E12.5. This allele is a hypomorph.
(J:93444)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Myf6
(mouse)
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Original: |
J:93444 Keller C, et al., Alveolar rhabdomyosarcomas in conditional Pax3:Fkhr mice: cooperativity of Ink4a/ARF and Trp53 loss of function. Genes Dev. 2004 Dec 1;18(21):2614-26 |
All: |
7 reference(s) |
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