Tg(CAG-rtTA)72Wiek
Transgene Detail

Summary

• Symbol: Tg(CAG-rtTA)72Wiek
• Name: transgene insertion 72, Maria T Wiekowski
• MGI ID: MGI:3779019
• Synonyms: CAG-rtTA, CMV-Betaactin-rtTA, Tg(ACTB-rtTA)72Wiek
• Transgene: Tg(CAG-rtTA)72Wiek Location: unknown
• Alliance: Tg(CAG-rtTA)72Wiek page

Transgene origin

• Strain of Origin: (C57BL/6J X DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Mutation details: The transgene construct contains the rtTA cDNA driven by the CMV enhancer/chicken beta-actin promoter. The rabbit beta-globin polyadenylation signal is also part of the transgene construct. Eight transgenic lines were derived, and line 72 was analyzed further based on high expression of activator transgene expression. (J:73096)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:73096 Wiekowski MT, et al., Disruption of neutrophil migration in a conditional transgenic model: evidence for CXCR2 desensitization in vivo. J Immunol. 2001 Dec 15;167(12):7102-10
• All: 4 reference(s)