Tg(CD2-Ahr*)NKno
Transgene Detail

Summary

• Symbol: Tg(CD2-Ahr*)NKno
• Name: transgene insertion N, Keiko Nohara
• MGI ID: MGI:3776517
• Synonyms: Tg(hCD2-CA-AhR)N
• Transgene: Tg(CD2-Ahr*)NKno Location: unknown
• Alliance: Tg(CD2-Ahr*)NKno page

Transgene origin

• Strain of Origin: C57BL/6J x DBA/2

Transgene description

• Transgene Type: Transgenic (Constitutively active, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The transgene contains the human CD2 promoter driving expression of a constitutively active mouse aryl hydrocarbon receptor. Line N was estimated to contain 6-7 transgene copies based on Southern blot analysis. Expression was confirmed in spleen and thymus. (J:97720)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:97720 Nohara K, et al., Constitutively active aryl hydrocarbon receptor expressed specifically in T-lineage cells causes thymus involution and suppresses the immunization-induced increase in splenocytes. J Immunol. 2005 Mar 1;174(5):2770-7
• All: 1 reference(s)