Gpr50^tm1Dgen
Targeted Allele Detail

Summary

• Symbol: Gpr50^tm1Dgen
• Name: G-protein-coupled receptor 50; targeted mutation 1, Deltagen
• MGI ID: MGI:3775916
• Synonyms: GPR50 KO
• Gene: Gpr50 Location: ChrX:70707273-70712863 bp, + strand Genetic Position: ChrX, 36.98 cM
• Alliance: Gpr50^tm1Dgen page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132163
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified
• Project Collection: Deltagen

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 and part of exon 2 were replaced with a lacZ-neo cassette. Expression of the lacZ gene was confirmed by in situ hybridization. (J:132163)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr50 Mutation: 7 strains or lines available

References

• Original: J:132163 Barrett P, et al., Photoperiodic regulation of cellular retinoic acid-binding protein 1, GPR50 and nestin in tanycytes of the third ventricle ependymal layer of the Siberian hamster. J Endocrinol. 2006 Dec;191(3):687-98
• All: 5 reference(s)