Foxa2tm2(cre/Esr1*)Moon
Targeted Allele Detail
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Symbol: |
Foxa2tm2(cre/Esr1*)Moon |
Name: |
forkhead box A2; targeted mutation 2, Anna M Moon |
MGI ID: |
MGI:3774419 |
Synonyms: |
Foxa2mcm-neo, Foxa2tm2(cre/Esr1*)Moon |
Gene: |
Foxa2 Location: Chr2:147884797-147888889 bp, - strand Genetic Position: Chr2, 73.38 cM
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Alliance: |
Foxa2tm2(cre/Esr1*)Moon page
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Germline Transmission: |
Earliest citation of germline transmission:
J:130990
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Hypomorph, Inducible, Recombinase) |
Inducer: |
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tamoxifen |
Mutation: |
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Insertion
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Foxa2tm2(cre/Esr1*)Moon expression driven by
1 gene
Knock-in expression driven by:
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Mutation details: An IRES followed by a mouse Esr1 binding domain fused to both sides of cre and an frt-flanked neo cassette was inserted in frame following the stop codon in exon 3. This allele is a hypomorph.
(J:130990)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Foxa2
(mouse)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Foxa2 Mutation: |
26 strains or lines available
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Original: |
J:130990 Park EJ, et al., System for tamoxifen-inducible expression of cre-recombinase from the Foxa2 locus in mice. Dev Dyn. 2008 Feb;237(2):447-53 |
All: |
2 reference(s) |
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