Kcnk3^tm1Daba
Targeted Allele Detail

Summary

• Symbol: Kcnk3^tm1Daba
• Name: potassium channel, subfamily K, member 3; targeted mutation 1, Douglas A Bayliss
• MGI ID: MGI:3774329
• Synonyms: TASK-1^f
• Gene: Kcnk3 Location: Chr5:30745514-30782614 bp, + strand Genetic Position: Chr5, 16.68 cM, cytoband B
• Alliance: Kcnk3^tm1Daba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130850
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2 and an additional loxP site was inserted downstream of exon 2. (J:130850)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kcnk3 Mutation: 34 strains or lines available

References

• Original: J:130850 Mulkey DK, et al., TASK channels determine pH sensitivity in select respiratory neurons but do not contribute to central respiratory chemosensitivity. J Neurosci. 2007 Dec 19;27(51):14049-58
• All: 4 reference(s)