Foxc1^tm1Tsku
Targeted Allele Detail

Summary

• Symbol: Foxc1^tm1Tsku
• Name: forkhead box C1; targeted mutation 1, Tsutomu Kume
• MGI ID: MGI:3773756
• Synonyms: Foxc1^flx
• Gene: Foxc1 Location: Chr13:31990629-31994618 bp, + strand Genetic Position: Chr13, 13.52 cM
• Alliance: Foxc1^tm1Tsku page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131323
• Parent Cell Line: TL1/TL-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: An FRT-flanked neo cassette with a 3' loxP site was inserted upstream of the coding sequence. An additional loxP site was inserted downstream of the coding sequence. Flp-mediated recombination removed the neo cassette. (J:188816)

Generation of the Foxc1^tm1Tsku and Foxc1^tm1.1Tsku alleles

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxc1 Mutation: 29 strains or lines available

References

• Original: J:131323 Hayashi H, et al., Forkhead transcription factors regulate expression of the chemokine receptor CXCR4 in endothelial cells and CXCL12-induced cell migration. Biochem Biophys Res Commun. 2008 Mar 14;367(3):584-9
• All: 20 reference(s)