Popdc2^tm1Tbd
Targeted Allele Detail

Summary

• Symbol: Popdc2^tm1Tbd
• Name: popeye domain containing 2; targeted mutation 1, Thomas Brand
• MGI ID: MGI:3773727
• Synonyms: Popdc2 deltaneo
• Gene: Popdc2 Location: Chr16:38182571-38198578 bp, + strand Genetic Position: Chr16, 26.79 cM
• Alliance: Popdc2^tm1Tbd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:131297
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: 490 bp of exon 1 and 27 bp of intron 1 were replaced with a nuclear localization signal-beta-galactosidase reporter gene construct. The floxed neo cassette contained within the insert was subsequently removed by cre-mediated recombination. Northern blot analysis confirmed the absence of transcript expression in skeletal muscle, heart and bladder. (J:131297, J:184566)

Expression

In Mice Carrying this Mutation:	111 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Popdc2 Mutation: 13 strains or lines available

References

• Original: J:131297 Froese A, et al., Expression pattern of Popdc2 during mouse embryogenesis and in the adult. Dev Dyn. 2008 Mar;237(3):780-7
• All: 2 reference(s)