Rasa1^tm1Pdk
Targeted Allele Detail

Summary

• Symbol: Rasa1^tm1Pdk
• Name: RAS p21 protein activator 1; targeted mutation 1, Philip D King
• MGI ID: MGI:3772459
• Synonyms: rasa1^fl
• Gene: Rasa1 Location: Chr13:85362899-85437249 bp, - strand Genetic Position: Chr13, 45.05 cM
• Alliance: Rasa1^tm1Pdk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:130493
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An frt-flanked neo cassette was inserted into intron 18 and an additional loxP site was inserted into intron 17. The neo cassette was removed by germ-line, flp-mediated recombination. (J:130493)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasa1 Mutation: 32 strains or lines available

References

• Original: J:130493 Lapinski PE, et al., Generation of mice with a conditional allele of the p120 Ras GTPase-activating protein. Genesis. 2007 Dec;45(12):762-7
• All: 11 reference(s)