Tg(PCK2-IGF2)525-41Ewo
Transgene Detail

Summary

• Symbol: Tg(PCK2-IGF2)525-41Ewo
• Name: transgene insertion 525-41, Eckhard Wolf
• MGI ID: MGI:3771173
• Transgene: Tg(PCK2-IGF2)525-41Ewo Location: unknown
• Alliance: Tg(PCK2-IGF2)525-41Ewo page

Transgene origin

• Strain of Origin: B6D2F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(PCK2-IGF2)525-41Ewo expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IGF2 (3481)

  Igf2	(MGI:96434)

• Mutation details: The transgene construct consists of 550 bp of the PEPCK promoter, 120 bp rat insulin II intron A sequences, the human IGF-II coding region, and 420 bp of the terminating sequences of the human growth hormone gene. (J:97243)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:97243 Wolf E, et al., Consequences of postnatally elevated insulin-like growth factor-II in transgenic mice: endocrine changes and effects on body and organ growth. Endocrinology. 1994 Nov;135(5):1877-86
• All: 4 reference(s)