Nacc1^tm1Jabl
Targeted Allele Detail

Summary

• Symbol: Nacc1^tm1Jabl
• Name: nucleus accumbens associated 1, BEN and BTB (POZ) domain containing; targeted mutation 1, Julie A Blendy
• MGI ID: MGI:3767840
• Synonyms: Nac1^-
• Gene: Nacc1 Location: Chr8:85397106-85414528 bp, - strand Genetic Position: Chr8, 41.02 cM
• Alliance: Nacc1^tm1Jabl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:128447
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A lacZ-neo cassette was inserted into exon 2 to create a null allele. The absence of protein was confirmed by western blot on nucleus accumbens and cortex. (J:128447)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nacc1 Mutation: 63 strains or lines available

References

• Original: J:128447 Mackler S, et al., Requirement for the POZ/BTB protein NAC1 in acute but not chronic psychomotor stimulant response. Behav Brain Res. 2008 Feb 11;187(1):48-55
• All: 2 reference(s)