Kiss1r^tm1Rla
Targeted Allele Detail

Summary

• Symbol: Kiss1r^tm1Rla
• Name: KISS1 receptor; targeted mutation 1, Risto Lapatto
• MGI ID: MGI:3762756
• Gene: Kiss1r Location: Chr10:79752805-79758107 bp, + strand Genetic Position: Chr10, 39.72 cM
• Alliance: Kiss1r^tm1Rla page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:126704
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced by a neomycin resistance cassette. A lack of gene expression was confirmed through RT-PCR. (J:126704)

Disease models

Expression

In Structures Affected by this Mutation:

11 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kiss1r Mutation: 20 strains or lines available

References

• Original: J:126704 Lapatto R, et al., Kiss1-/- mice exhibit more variable hypogonadism than Gpr54-/- mice. Endocrinology. 2007 Oct;148(10):4927-36
• All: 3 reference(s)