Mrgprb4^tm1And
Targeted Allele Detail

Summary

• Symbol: Mrgprb4^tm1And
• Name: MAS-related GPR, member B4; targeted mutation 1, David J Anderson
• MGI ID: MGI:3721921
• Synonyms: MrgprB4delta^PLAP
• Gene: Mrgprb4 Location: Chr7:47847961-47848926 bp, - strand Genetic Position: Chr7, 31.11 cM
• Alliance: Mrgprb4^tm1And page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:124203
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The entire open reading frame of the locus was replaced by a PLAP gene and pGK-Hyg selection cassette. The expression of the PLAP gene in heterozygous mice was coincident with that of endogenous gene, as determined by double label in situ hybridization. (J:124203)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mrgprb4 Mutation: 25 strains or lines available

References

• Original: J:124203 Liu Q, et al., Molecular genetic visualization of a rare subset of unmyelinated sensory neurons that may detect gentle touch. Nat Neurosci. 2007 Aug;10(8):946-8
• All: 3 reference(s)