Ehmt2^tm2Yshk
Targeted Allele Detail

Summary

• Symbol: Ehmt2^tm2Yshk
• Name: euchromatic histone lysine N-methyltransferase 2; targeted mutation 2, Yoichi Shinkai
• MGI ID: MGI:3718575
• Synonyms: G9a^cnd, G9a^flox
• Gene: Ehmt2 Location: Chr17:35117445-35133028 bp, + strand Genetic Position: Chr17, 18.45 cM
• Alliance: Ehmt2^tm2Yshk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:123269
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exon 26, a cDNA for exons 27/28, and a PGK-neo cassette were flanked by two loxP sites. (J:123269)

Expression

In Mice Carrying this Mutation:	26 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ehmt2 Mutation: 55 strains or lines available

References

• Original: J:123269 Tachibana M, et al., Functional dynamics of H3K9 methylation during meiotic prophase progression. EMBO J. 2007 Jul 25;26(14):3346-59
• All: 15 reference(s)