Shisa5^tm1Sia
Targeted Allele Detail

Summary

• Symbol: Shisa5^tm1Sia
• Name: shisa family member 5; targeted mutation 1, Shinichi Aizawa
• MGI ID: MGI:3715226
• Synonyms: mShisa5^lacZ
• Gene: Shisa5 Location: Chr9:108867633-108886845 bp, + strand Genetic Position: Chr9, 59.63 cM, cytoband F2
• Alliance: Shisa5^tm1Sia page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122557
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 through 6 were replaced with an IRES-lacZ-neo cassette creating a null allele. No beta-galactosidase activity was detected. (J:122557)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Shisa5 Mutation: 18 strains or lines available

References

• Original: J:122557 Furushima K, et al., Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings. Dev Biol. 2007 Jun 15;306(2):480-92
• All: 1 reference(s)