Grin2b^tm3Mim
Targeted Allele Detail

Summary

• Symbol: Grin2b^tm3Mim
• Name: glutamate receptor, ionotropic, NMDA2B (epsilon 2); targeted mutation 3, Masayoshi Mishina
• MGI ID: MGI:3715219
• Synonyms: GluRepsilon2^floxed
• Gene: Grin2b Location: Chr6:135690231-136150509 bp, - strand Genetic Position: Chr6, 66.38 cM
• Alliance: Grin2b^tm3Mim page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122587
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Two loxP sites were inserted 5' of exon 12 along with an frt-flanked neo cassette and another loxP site 3' of exon 12. (J:122587)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grin2b Mutation: 100 strains or lines available

References

• Original: J:122587 Mishina M, et al., Conditional gene targeting on the pure C57BL/6 genetic background. Neurosci Res. 2007 Jun;58(2):105-12
• All: 2 reference(s)