Trib3^tm1Mws
Targeted Allele Detail

Summary

• Symbol: Trib3^tm1Mws
• Name: tribbles pseudokinase 3; targeted mutation 1, Mark W Sleeman
• MGI ID: MGI:3713755
• Synonyms: Trib3^-
• Gene: Trib3 Location: Chr2:152179342-152185952 bp, - strand Genetic Position: Chr2, 74.83 cM
• Alliance: Trib3^tm1Mws page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:122116
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The open reading frame was replaced with a LacZ-neo cassette to create a null allele. The absence of protein product was confirmed by western blot analysis. (J:122116)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trib3 Mutation: 17 strains or lines available

References

• Original: J:122116 Okamoto H, et al., Genetic deletion of Trb3, the mammalian Drosophila tribbles homolog, displays normal hepatic insulin signaling and glucose homeostasis. Diabetes. 2007 May;56(5):1350-6
• All: 6 reference(s)