Gabpa^tm1Pjh
Targeted Allele Detail

Summary

• Symbol: Gabpa^tm1Pjh
• Name: GA repeat binding protein, alpha; targeted mutation 1, Paul J Hertzog
• MGI ID: MGI:3711315
• Gene: Gabpa Location: Chr16:84631813-84660667 bp, + strand Genetic Position: Chr16, 46.92 cM, cytoband C3-4
• Alliance: Gabpa^tm1Pjh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:121356
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• A targeting vector was designed to insert loxP sites to flank exon 2, the first coding exon. (J:121356)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gabpa Mutation: 66 strains or lines available

References

• Original: J:121356 O'Leary DA, et al., Targeting of the ETS factor GABPalpha disrupts neuromuscular junction synaptic function. Mol Cell Biol. 2007 May;27(9):3470-80
• All: 1 reference(s)