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Slc16a2tm1Dgen
Targeted Allele Detail
Summary
Symbol: Slc16a2tm1Dgen
Name: solute carrier family 16 (monocarboxylic acid transporters), member 2; targeted mutation 1, Deltagen
MGI ID: MGI:3710233
Synonyms: Mct8-
Gene: Slc16a2  Location: ChrX:102741020-102865589 bp, - strand  Genetic Position: ChrX, 46.29 cM
Alliance: Slc16a2tm1Dgen page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:120737
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Project Collection: Deltagen
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 33 bp-fragment of exon 2 was replaced with a lacZ-neo cassette. Absence of protein was confirmed by Western blot of mutant liver homogenates. (J:120737)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 8 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Slc16a2 Mutation:  9 strains or lines available
References
Original:  J:120737 Trajkovic M, et al., Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8. J Clin Invest. 2007 Mar;117(3):627-35
All:  18 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory