Tg(Crx-GFP,-ALPP)1Clc
Transgene Detail

Summary

• Symbol: Tg(Crx-GFP,-ALPP)1Clc
• Name: transgene insertion 1, Constance L Cepko
• MGI ID: MGI:3709032
• Synonyms: Crx GFPAP
• Transgene: Tg(Crx-GFP,-ALPP)1Clc Location: unknown
• Alliance: Tg(Crx-GFP,-ALPP)1Clc page

Transgene origin

• Strain of Origin: SJL

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A loxP-flanked kanamycin/neomycin drug resistance cassette and a GFP/IRES/PLAP fragment were targeted to replace the first exon of the mouse Crx gene in a BAC clone by ET-cloning. Cre was activated in the EL250 bacterial host strain with arabinose to remove the floxed kanamycin/neomycin segment, and the resultant BAC was digested with NotI to generate a transgenic fragment. (J:120988)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:120988 Cepko CL, A mouse expressing a Crx-driven dual reporter transgene. MGI Direct Data Submission. 2007
• All: 1 reference(s)