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Isxtm1Shiv
Targeted Allele Detail
Summary
Symbol: Isxtm1Shiv
Name: intestine specific homeobox; targeted mutation 1, Ramesh A Shivadaani
MGI ID: MGI:3703167
Synonyms: Isx-
Gene: Isx  Location: Chr8:75599801-75620134 bp, + strand  Genetic Position: Chr8, 35.54 cM, cytoband C2
Alliance: Isxtm1Shiv page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:119560
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a neomycin resistance cassette. Northern blot confirmed absence of transcript in mutant cecum and stomach samples. (J:119560)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 9 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Isx Mutation:  23 strains or lines available
References
Original:  J:119560 Choi MY, et al., A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development. Development. 2006 Oct;133(20):4119-29
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/28/2024
MGI 6.13
The Jackson Laboratory