Nmur2^m1Hzg
Transgenic Allele Detail

Summary

• Symbol: Nmur2^m1Hzg
• Name: neuromedin U receptor 2; mutation 1, Hongkui Zheng
• MGI ID: MGI:3701426
• Synonyms: NMUR2 KO
• Gene: Nmur2 Location: Chr11:55915816-55931813 bp, - strand Genetic Position: Chr11, 33.39 cM
• Alliance: Nmur2^m1Hzg page

Transgene origin

• Germline Transmission: Earliest citation of germline transmission: J:117649
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Transgene description

• Transgene Type: Transgenic (Null/knockout)
• Mutation: Viral insertion
• Mutation details: A retroviral vector was inserted into the third intron and contained a splice acceptor, termination codons in all reading frames, a selection marker and a transcription terminator. This design would interrupt the transcript before exon 4, which contains TM7 of the 7-transmembrane domain and the C-terminal domain. RT-PCR confirmed absence of wild-type transcript in mutants. (J:117649)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmur2 Mutation: 27 strains or lines available

References

• Original: J:117649 Zeng H, et al., Neuromedin U receptor 2-deficient mice display differential responses in sensory perception, stress, and feeding. Mol Cell Biol. 2006 Dec;26(24):9352-63
• All: 1 reference(s)