Rr151^tm1Bgmn
Targeted Allele Detail

Summary

• Symbol: Rr151^tm1Bgmn
• Name: regulatory region 151; targeted mutation 1, Marianne Bruggemann
• MGI ID: MGI:3701073
• Synonyms: 3'E^lox, Ighm^tm1Bgmn
• Gene: Rr151 Location: unknown Genetic Position: Chr12, Syntenic
• Alliance: Rr151^tm1Bgmn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:118453
• Parent Cell Line: ZX3 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Modified regulatory region)
• Mutation: Insertion
• Mutation details: A neomycin resistance gene cassette with a 3' loxP site was introduced into the alpha 3' enhancer ~15 kb downstream of the Igh Calpha segment. (J:118453)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr151 Mutation: 0 strains or lines available

References

• Original: J:118453 Ren L, et al., Silencing of the immunoglobulin heavy chain locus by removal of all eight constant-region genes in a 200-kb region. Genomics. 2004 Oct;84(4):686-95
• All: 1 reference(s)