Tg(APOA1-Scarb1)B2614Hgc
Transgene Detail

Summary

• Symbol: Tg(APOA1-Scarb1)B2614Hgc
• Name: transgene insertion B2614, Edward M Rubin
• MGI ID: MGI:3699594
• Transgene: Tg(APOA1-Scarb1)B2614Hgc Location: unknown
• Alliance: Tg(APOA1-Scarb1)B2614Hgc page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(APOA1-Scarb1)B2614Hgc expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Scarb1 (MGI:893578)

• Mutation details: The transgenic construct contains the human APOA1 promoter from nucleotides 21613 to 172 of the transcription start site fused to a mouse Scarb1 genomic fragment at its initiation codon. (J:53939)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:53939 Ueda Y, et al., Lower plasma levels and accelerated clearance of high density lipoprotein (HDL) and non-HDL cholesterol in scavenger receptor class B type I transgenic mice. J Biol Chem. 1999 Mar 12;274(11):7165-71
• All: 2 reference(s)