Tg(KB1430A10)1Ped
Transgene Detail

Summary

• Symbol: Tg(KB1430A10)1Ped
• Name: transgene insertion 1, Peter A Edwards
• MGI ID: MGI:3695585
• Synonyms: ABCG1-transgenic
• Transgene: Tg(KB1430A10)1Ped Location: unknown
• Alliance: Tg(KB1430A10)1Ped page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KB1430A10)1Ped expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ABCG1 (9619)

  Abcg1

  (MGI:107704)

• Mutation details: A 145 kb BAC clone (KB1430A10) containing 100 kb of the human ABCG1 gene plus an additional 35 kb 5' and 10 kb to 3' to the gene was purified and injected into fertilized C57BL/6 eggs. (J:117028)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:117028 Kennedy MA, et al., ABCG1 has a critical role in mediating cholesterol efflux to HDL and preventing cellular lipid accumulation. Cell Metab. 2005 Feb;1(2):121-31
• All: 1 reference(s)