Trp53^tm4Wahl
Targeted Allele Detail

Summary

• Symbol: Trp53^tm4Wahl
• Name: transformation related protein 53; targeted mutation 4, Geoffrey M Wahl
• MGI ID: MGI:3693644
• Synonyms: P53^deltaPGFP
• Gene: Trp53 Location: Chr11:69471185-69482699 bp, + strand Genetic Position: Chr11, 42.83 cM, cytoband B2-C
• Alliance: Trp53^tm4Wahl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116011
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S4/SvJae

Mutation description

• Allele Type: Targeted (RMCE-ready, Reporter)
• Mutation: Insertion
• Mutation details: Recombinase-mediated cassette exchange was used to insert a GFP gene into the locus with a modified exon 4 lacking the proline rich domain (p.E75_S91del). (J:116011)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trp53 Mutation: 237 strains or lines available

References

• Original: J:116011 Toledo F, et al., RMCE-ASAP: a gene targeting method for ES and somatic cells to accelerate phenotype analyses. Nucleic Acids Res. 2006;34(13):e92
• All: 1 reference(s)