Hand1^tm1(tTA)Prri
Targeted Allele Detail

Summary

• Symbol: Hand1^tm1(tTA)Prri
• Name: heart and neural crest derivatives expressed 1; targeted mutation 1, Paul R Riley
• MGI ID: MGI:3693329
• Gene: Hand1 Location: Chr11:57719539-57722973 bp, - strand Genetic Position: Chr11, 35.27 cM
• Alliance: Hand1^tm1(tTA)Prri page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:116090
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Transactivator)
• Mutation: Insertion
• Mutation details: The tTA transactivator was inserted into the locus with a floxed neo cassette. The tTA transactivator is epxressed in an equivalent spatial pattern to endogenous Hand1. (J:116090)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hand1 Mutation: 14 strains or lines available

References

• Original: J:116090 Risebro CA, et al., Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart. Development. 2006 Nov;133(22):4595-606
• All: 1 reference(s)