Ybx3^tm1Ley
Targeted Allele Detail

Summary

• Symbol: Ybx3^tm1Ley
• Name: Y box protein 3; targeted mutation 1, Timothy J Ley
• MGI ID: MGI:3693011
• Synonyms: Msy4^-
• Gene: Ybx3 Location: Chr6:131341821-131365413 bp, - strand Genetic Position: Chr6, 63.44 cM
• Alliance: Ybx3^tm1Ley page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115970
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 2-5 were replaced with a PGK-neo cassette. Western blot failed to detect protein in mutants. (J:115970)

Expression

In Mice Carrying this Mutation:	22 assay results
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ybx3 Mutation: 30 strains or lines available

References

• Original: J:115970 Lu ZH, et al., Cold shock domain family members YB-1 and MSY4 share essential functions during murine embryogenesis. Mol Cell Biol. 2006 Nov;26(22):8410-7
• All: 2 reference(s)