Tg(Agrp-cre)2Gsb
Transgene Detail

Summary

• Symbol: Tg(Agrp-cre)2Gsb
• Name: transgene insertion 2, Gregory S Barsh
• MGI ID: MGI:3688399
• Synonyms: Tg.AgrpCre
• Transgene: Tg(Agrp-cre)2Gsb Location: unknown
• Alliance: Tg(Agrp-cre)2Gsb page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Agrp-cre)2Gsb expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Agrp

• Mutation details: A cDNA encoding codon-improved cre (iCre) recombinase with an IVSpA sequence was placed immediately upstream of the normal translational initiation site in exon 2 of the agouti related protein in a BAC clone. (J:112931)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Agrp (species not specified) Summary of all recombinase alleles driven by Agrp. Comparative matrix view of recombinase activities

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:112931 Kaelin CB, et al., Signal transducer and activator of transcription (stat) binding sites but not stat3 are required for fasting-induced transcription of agouti-related protein messenger ribonucleic acid. Mol Endocrinol. 2006 Oct;20(10):2591-602
• All: 9 reference(s)