S100gdel1
Spontaneous Allele Detail
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Symbol: |
S100gdel1 |
Name: |
S100 calcium binding protein G; deletion 1 |
MGI ID: |
MGI:3665167 |
Gene: |
S100g Location: ChrX:161744988-161747595 bp, - strand Genetic Position: ChrX, 75.15 cM
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Alliance: |
S100gdel1 page
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Germline Transmission: |
Earliest citation of germline transmission:
J:111779
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Spontaneous |
Mutation: |
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Intragenic deletion
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Mutation details: The E14.1 ES cell line harbors a spontaneous mutation in this gene. It is not present in the parental 129P2/OlaHsd strain from which the E14.1 ES line is derived. A deletion of 22 nt in exon III results in a frameshift, thereby creating a new in-frame stop codon 63 nt downstream of the original stop codon. Western blot analysis on mutant duodenum lysates confirmed that no detectable protein is expressed from this allele.
(J:111779)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any S100g Mutation: |
2 strains or lines available
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Original: |
J:111779 Kutuzova GD, et al., Calbindin D9k knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12377-81 |
All: |
5 reference(s) |
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