S100g^del1
Spontaneous Allele Detail

Summary

• Symbol: S100g^del1
• Name: S100 calcium binding protein G; deletion 1
• MGI ID: MGI:3665167
• Gene: S100g Location: ChrX:161744988-161747595 bp, - strand Genetic Position: ChrX, 75.15 cM
• Alliance: S100g^del1 page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111779
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Spontaneous
• Mutation: Intragenic deletion
• Mutation details: The E14.1 ES cell line harbors a spontaneous mutation in this gene. It is not present in the parental 129P2/OlaHsd strain from which the E14.1 ES line is derived. A deletion of 22 nt in exon III results in a frameshift, thereby creating a new in-frame stop codon 63 nt downstream of the original stop codon. Western blot analysis on mutant duodenum lysates confirmed that no detectable protein is expressed from this allele. (J:111779)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S100g Mutation: 3 strains or lines available

References

• Original: J:111779 Kutuzova GD, et al., Calbindin D9k knockout mice are indistinguishable from wild-type mice in phenotype and serum calcium level. Proc Natl Acad Sci U S A. 2006 Aug 15;103(33):12377-81
• All: 5 reference(s)