Pmm1^tm1Gmat
Targeted Allele Detail

Summary

• Symbol: Pmm1^tm1Gmat
• Name: phosphomannomutase 1; targeted mutation 1, G Matthijs
• MGI ID: MGI:3663169
• Synonyms: Pmm1^-
• Gene: Pmm1 Location: Chr15:81835309-81845131 bp, - strand Genetic Position: Chr15, 38.3 cM
• Alliance: Pmm1^tm1Gmat page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111419
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: A neomycin resistance cassette was inserted into exon 3. Absence of protein was demonstrated by Western blot of mutant brain homogenates. (J:111419)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pmm1 Mutation: 33 strains or lines available

References

• Original: J:111419 Cromphout K, et al., The normal phenotype of Pmm1-deficient mice suggests that Pmm1 is not essential for normal mouse development. Mol Cell Biol. 2006 Aug;26(15):5621-35
• All: 1 reference(s)