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Transgene Detail
Symbol: Tg(tetO-Ipf1,EGFP)956.6Macd
Name: transgene insertion 956-6, Raymond J MacDonald
MGI ID: MGI:3655514
Synonyms: Pdx1-EGFP, Pdx1-GFP, Pdx1Tg, tetO-Pdx1, tetO-Pdx1-EGFP, tetO-Pdx1/EGFP, tetO/Pdx1/EGFP, TgPdx1, tTA-responsive Pdx1-EGFP
Transgene: Tg(tetO-Ipf1,EGFP)956.6Macd  Location: unknown  
Alliance: Tg(tetO-Ipf1,EGFP)956.6Macd page
Strain of Origin:  (C57BL/6 x SJL)F2
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence, Reporter)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
Mutation detailsA transgenic vector containing an Ipf1 minigene (both exons of Ipf1 linked by a shortened exon and preceded by a truncated 5' UTR and an IRES-linked EGFP reporter) under control of seven direct repeats of the tetracycline operator (tetO) fused to the human cytomegalovirus (hCMV) immediate early promoter. High expression of Ipf1 and EGFP is induced by the introduction of the tetracycline-transactivator protein by breeding with an appropriate mouse line. (J:79206)
View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Original:  J:79206 Holland AM, et al., Experimental control of pancreatic development and maintenance. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12236-41
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
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