Ufd1^tm1Bld
Targeted Allele Detail

Summary

• Symbol: Ufd1^tm1Bld
• Name: ubiquitin recognition factor in ER-associated degradation 1; targeted mutation 1, Antonio Baldini
• MGI ID: MGI:3640091
• Synonyms: Ufd1l-
• Gene: Ufd1 Location: Chr16:18630529-18654011 bp, + strand Genetic Position: Chr16, 11.65 cM, cytoband B1-B4
• Alliance: Ufd1^tm1Bld page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:57757
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: A targeting vector with the Hprt delta5' cassette and a loxP site was used to replace a 4.5kb region containing exons 2-3 of Ufd1l. The Udf1l^tm1Bld mutant allele was created in the double-targeted cell line 217 which was originally derived from AB2.2 ES cells J:57757. (J:57757)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ufd1 Mutation: 30 strains or lines available

References

• Original: J:57757 Lindsay EA, et al., Congenital heart disease in mice deficient for the DiGeorge syndrome region [see comments]. Nature. 1999 Sep 23;401(6751):379-83
• All: 1 reference(s)