Lmo7tm1Tilg
Targeted Allele Detail
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Symbol: |
Lmo7tm1Tilg |
Name: |
LIM domain only 7; targeted mutation 1, Shirley M Tilghman |
MGI ID: |
MGI:3639949 |
Synonyms: |
Lmodelta800 |
Gene: |
Lmo7 Location: Chr14:101967393-102172146 bp, + strand Genetic Position: Chr14, 50.9 cM
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Alliance: |
Lmo7tm1Tilg page
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Germline Transmission: |
Earliest citation of germline transmission:
J:83810
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Parent Cell Line: |
AB2.2 (ES Cell)
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Strain of Origin: |
129S7/SvEvBrd-Hprt1b-m2
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Allele Type: |
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Targeted (Null/knockout) |
Mutation: |
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Intergenic deletion
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Mutation details: An 800kb deletion including the last 8 exons of Uchl3 and the entire Lmo7 gene was created using Cre-loxP recombination in ES cells to insert loxP sites at the breakpoints of the intended deletion. Targeting vectors were injected into AB2.2 ES cells and correctly targeted clones were electroporated with a Cre-expressing plasmid to excise the 800kb region.
(J:83810)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lmo7 Mutation: |
104 strains or lines available
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Original: |
J:83810 Semenova E, et al., An engineered 800 kilobase deletion of Uchl3 and Lmo7 on mouse chromosome 14 causes defects in viability, postnatal growth and degeneration of muscle and retina. Hum Mol Genet. 2003 Jun 1;12(11):1301-12 |
All: |
1 reference(s) |
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