Pcdh8^tm1Emdr
Targeted Allele Detail

Summary

• Symbol: Pcdh8^tm1Emdr
• Name: protocadherin 8; targeted mutation 1, E M De Robertis
• MGI ID: MGI:3630287
• Synonyms: papc KO
• Gene: Pcdh8 Location: Chr14:80004224-80008752 bp, - strand Genetic Position: Chr14, 42.76 cM
• Alliance: Pcdh8^tm1Emdr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:63695
• Parent Cell Line: RW-4 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A GFP-neomycin selection/expression cassette replaced a 2.8 kb region of the coding sequence, including the translation initiation site in exon 1 through the end of the cytoplasmic domain in exon 3. GFP was inserted in-frame to the coding region of the gene, but is not expressed from this allele. (J:63695)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdh8 Mutation: 36 strains or lines available

References

• Original: J:63695 Yamamoto A, et al., Mouse paraxial protocadherin is expressed in trunk mesoderm and is not essential for mouse development. Genesis. 2000 Jun;27(2):49-57
• All: 4 reference(s)