Hr^rh-Y
Spontaneous Allele Detail

Summary

• Symbol: Hr^rh-Y
• Name: lysine demethylase and nuclear receptor corepressor; rhino Yurlovo
• MGI ID: MGI:3630274
• Synonyms: hr^rhY
• Gene: Hr Location: Chr14:70789652-70810988 bp, + strand Genetic Position: Chr14, 36.32 cM
• Alliance: Hr^rh-Y page

Mutation origin

• Strain of Origin: B10.R109/Y

Mutation description

• Allele Type: Spontaneous
• Mutation: Insertion
• Mutation details: The mutation is a 13 bp insertion into the coding sequence of exon 16. This results in a frameshift and premature truncation of the encoded protein. (J:53634)

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hr Mutation: 84 strains or lines available

References

• Original: J:53634 Panteleyev AA, et al., Molecular basis for the rhino Yurlovo (hr(rhY)) phenotype: severe skin abnormalities and female reproductive defects associated with an insertion in the hairless gene. Exp Dermatol. 1998 Oct;7(5):281-8
• All: 1 reference(s)